Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224713 | 0.90 | PTGDR2 (0.35) | PTGDR2MEN1KMT2A | |
| SCHEMBL509764 | 0.84 | ALDH1A1 (0.39) | PTGDR2CNR1LMNARXFP1KMT2A | |
| SCHEMBL5226561 | 0.83 | PTGDR2 (0.35) | PTGDR2 | |
| SCHEMBL5228699 | 0.82 | POLB (0.36) | PTGDR2CNR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL12133533 | 0.79 | POLB (0.32) | PTGDR2CNR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL5233666 | 0.77 | PTGDR2 (0.33) | PTGDR2 | |
| SCHEMBL5226341 | 0.76 | FAAH (0.33) | PTGDR2LMNAMEN1KMT2A | |
| SCHEMBL509028 | 0.74 | PTGDR2 (0.38) | PTGDR2MEN1KMT2ACARM1PRMT6 | |
| SCHEMBL5228035 | 0.71 | CACNA1G (0.41) | PTGDR2CNR1 | |
| SCHEMBL509007 | 0.69 | MAPT (0.36) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377556-B1 | PYRAZOLE DERIVATIVES FOR TREATING HIV | PFIZER LTD (GB) | 2007-04-04 | — | — | EP | claimed |