Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460509 | 0.84 | CSNK1D (0.42) | LMNANPC1RAB9ACCNA2CDK2 | |
| Ammonia Solution, Strong SCHEMBL28994883 | 0.82 | CSNK1D (0.41) | ALDH1A1LMNAKDM4ENPC1RAB9A | |
| SCHEMBL23397418 | 0.79 | ALDH1A1 (0.61) | ALDH1A1LMNAKDM4ENPSR1TDP1 | |
| SCHEMBL5227004 | 0.77 | NPC1 (0.62) | ALDH1A1LMNAKDM4ENPSR1TDP1 | |
| SCHEMBL28110823 | 0.76 | CCNA2 (0.55) | ALDH1A1LMNAKDM4ENPSR1TDP1 | |
| SCHEMBL5221958 | 0.75 | ALDH1A1 (0.51) | ALDH1A1LMNAKDM4ENPSR1TDP1 | |
| SCHEMBL14484701 | 0.75 | MAPT (0.46) | KDM4ENPSR1MAPTKMT2AABL1 | |
| SCHEMBL11819228 | 0.74 | ABL1 (0.73) | ALDH1A1LMNAKDM4ENPSR1TDP1 | |
| SCHEMBL10976797 | 0.74 | KDM4E (0.58) | ALDH1A1LMNAKDM4ENPSR1TDP1 | |
| SCHEMBL10991494 | 0.74 | KDM4E (0.58) | ALDH1A1LMNAKDM4ENPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300399-B1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2007-08-22 | — | — | EP | disclosed |
| US-6664256-B1 | Interleukin- 1 beta inhibitors | KOWA CO., LTD. (JP) | 2003-12-16 | — | — | US | disclosed |
| EP-1300399-A1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |