Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225875 | 0.81 | CYP2D6 (0.36) | CYP2D6SMO | |
| SCHEMBL2761237 | 0.78 | SMO (0.43) | LMNASMO | |
| SCHEMBL2761009 | 0.78 | SMO (0.43) | LMNASMO | |
| SCHEMBL2761177 | 0.78 | DRD4 (0.42) | SMO | |
| SCHEMBL5223970 | 0.77 | ADORA2A (0.40) | KCNH2LMNASMO | |
| Hydrochloric Acid SCHEMBL1997589 | 0.77 | SMO (0.42) | LMNASMO | |
| SCHEMBL5222786 | 0.76 | GRM2 (0.38) | KCNH2CYP2D6SMO | |
| SCHEMBL2761137 | 0.76 | SMO (0.41) | LMNASMO | |
| SCHEMBL5228002 | 0.75 | TSHR (0.39) | ACHESMO | |
| SCHEMBL5229287 | 0.75 | EGFR (0.40) | LMNASMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611122-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-06-13 | — | — | EP | disclosed |