Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 9/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224977 | 0.86 | NR1H4 (0.69) | NR1H4RXFP1RAB9ANPC1MEN1 | |
| SCHEMBL7243018 | 0.81 | NR1H4 (0.72) | NR1H4RXFP1RAB9ANPC1MEN1 | |
| SCHEMBL9851221 | 0.75 | LMNA (0.63) | NR1H4RAB9ANPC1MEN1POLB | |
| SCHEMBL7217502 | 0.73 | HPGD (0.61) | NR1H4RAB9ANPC1MEN1POLB | |
| SCHEMBL21652267 | 0.73 | KCNK3 (0.56) | RXFP1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL5223218 | 0.72 | NR1H4 (0.73) | NR1H4RXFP1RAB9ANPC1MEN1 | |
| SCHEMBL5226076 | 0.71 | NPC1 (0.71) | NR1H4RXFP1RAB9ANPC1MEN1 | |
| SCHEMBL24925441 | 0.71 | HDAC1 (0.54) | RAB9ANPC1HSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL5426350 | 0.71 | NPC1 (0.82) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL11204897 | 0.70 | NPC1 (0.70) | RXFP1RAB9ANPC1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |