SCHEMBL5225775

SCHEMBL5225775

NC(CO)Cc1cccc(Oc2ccccc2F)c1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 2/20 0.46
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
FFAR4 Q5NUL3 1/20 0.41
PARP10 Q53GL7 1/20 0.40
LPAR1 Q92633 5/20 0.40
LPAR5 Q9H1C0 5/20 0.40
TAAR1 Q96RJ0 2/20 0.40
CARM1 Q86X55 2/20 0.39
PRMT6 Q96LA8 2/20 0.39
PCNA P12004 1/20 0.39
LIG1 P18858 1/20 0.39
EPHX1 P07099 1/20 0.39
SCN9A Q15858 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5230197 0.83 EPHX1 (0.50) FDFT1PPARGPPARATAAR1PCNA
SCHEMBL2354368 0.81 TTR (0.50) FDFT1FFAR4PARP10LPAR1LPAR5
SCHEMBL8252058 0.80 FDFT1 (0.49) FDFT1PPARGPPARAFFAR4LPAR1
SCHEMBL922873 0.78 F10 (0.50) FDFT1FFAR4PARP10LPAR1LPAR5
Water SCHEMBL924179 0.77 F10 (0.49) FDFT1FFAR4PARP10LPAR1LPAR5
Hydrochloric Acid SCHEMBL921825 0.77 F10 (0.49) FDFT1FFAR4PARP10LPAR1LPAR5
SCHEMBL10904130 0.75 FDFT1 (0.49) FDFT1FFAR4PARP10LPAR1LPAR5
SCHEMBL29337151 0.75 TAAR1 (0.70) TAAR1
SCHEMBL8429259 0.75 FDFT1 (0.49) FDFT1FFAR4PARP10LPAR1LPAR5
SCHEMBL1191537 0.75 FDFT1 (0.49) FDFT1FFAR4PARP10LPAR1LPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1092435-B1 REMEDIES FOR DIABETES KYOWA HAKKO KOGYO KK (JP) 2007-04-04 EP disclosed
EP-1092435-A1 REMEDIES FOR DIABETES KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-04-18 EP disclosed