Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 2/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10904130 | 0.83 | FDFT1 (0.49) | FDFT1LPAR1LPAR5FFAR4HTT | |
| SCHEMBL922873 | 0.83 | F10 (0.50) | FDFT1LPAR1LPAR5FFAR4PARP10 | |
| SCHEMBL2354368 | 0.83 | TTR (0.50) | FDFT1LPAR1LPAR5FFAR4PARP10 | |
| SCHEMBL1191537 | 0.83 | FDFT1 (0.49) | FDFT1LPAR1LPAR5FFAR4HTT | |
| SCHEMBL10106199 | 0.83 | FDFT1 (0.56) | FDFT1LPAR1LPAR5 | |
| SCHEMBL8252058 | 0.83 | FDFT1 (0.49) | FDFT1LPAR1LPAR5FFAR4HTT | |
| Water SCHEMBL924179 | 0.82 | F10 (0.49) | FDFT1LPAR1LPAR5FFAR4PARP10 | |
| Hydrochloric Acid SCHEMBL921825 | 0.82 | F10 (0.49) | FDFT1LPAR1LPAR5FFAR4PARP10 | |
| SCHEMBL6290619 | 0.82 | PARP10 (0.50) | FDFT1PARP10ALDH1A1MEN1KMT2A | |
| SCHEMBL14266924 | 0.81 | AR (0.48) | FDFT1NPSR1KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9518000-B2 | Bicyclo [2.2.1] acid GPR120 modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-12-13 | — | — | US | disclosed |
| US-20160016880-A1 | BICYCLO [2.2.1] ACID GPR120 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2016-01-21 | — | — | US | disclosed |
| US-7786122-B2 | α-(N-sulfonamido)acetamide derivatives as β-amyloid inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-08-31 | — | — | US | disclosed |
| US-20080085894-A1 | ALPHA-(N-SULFONAMIDO)ACETAMIDE DERIVATIVES AS BETA-AMYLOID INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2008-04-10 | — | — | US | disclosed |
| US-20070191402-A1 | Method of searching substrate having antidiabetic activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20070191402-A1 | Method of searching substrate having antidiabetic activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191402-A1 | Method of searching substrate having antidiabetic activity | RNASE1, IAPP, AMY2A | FDFT1 2225/4885LPAR1 3444/4885LPAR5 3820/4885 |
| US-20080085894-A1 | ALPHA-(N-SULFONAMIDO)ACETAMIDE DERIVATIVES AS BETA-AMYLOID INHIBITORS | APP, APBA1, BACE1 | FDFT1 4216/4885LPAR1 3534/4885LPAR5 4562/4885 |
| US-20160016880-A1 | BICYCLO [2.2.1] ACID GPR120 MODULATORS | GPR180, GPR88, GPBAR1 | FDFT1 2633/4885LPAR1 40/4885LPAR5 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.