Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7243729 | 0.88 | ALDH1A1 (0.50) | CCR5ACHEACKR3MEN1KMT2A | |
| SCHEMBL5223734 | 0.78 | CHRM4 (0.51) | ACHEACKR3SIGMAR1MEN1KMT2A | |
| SCHEMBL7243422 | 0.76 | ACKR3 (0.49) | ACHEACKR3SIGMAR1MEN1KMT2A | |
| SCHEMBL7249999 | 0.76 | KDM4E (0.48) | ACHEACKR3MEN1KMT2AKDM4E | |
| SCHEMBL5227303 | 0.76 | CYP2D6 (0.49) | ACHEACKR3MEN1KMT2AKDM4E | |
| SCHEMBL7246833 | 0.76 | ACKR3 (0.48) | ACHEACKR3SIGMAR1MEN1KMT2A | |
| SCHEMBL7251452 | 0.75 | RAB9A (0.53) | ACKR3SIGMAR1MEN1KMT2AKDM4E | |
| SCHEMBL5226525 | 0.74 | PRKAB2 (0.52) | ACHEACKR3MEN1KMT2AKDM4E | |
| SCHEMBL5224692 | 0.74 | CYP3A4 (0.48) | ACHEACKR3MEN1KMT2A | |
| SCHEMBL5225093 | 0.74 | USP2 (0.50) | ACHEACKR3MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |