Dihydrolipoic Acid

Dihydrolipoic Acid

SCHEMBL5227074

O=C(O)CCCCC(=S)CC=S.O=C(O)CCCCC(S)CCS

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GSTK1 Q9Y2Q3 2/20 0.41
FOLH1 Q04609 5/20 0.40
ENPEP Q07075 4/20 0.40
ANPEP P15144 1/20 0.35
TYR P14679 1/20 0.34
LMNA P02545 2/20 0.33
FFAR4 Q5NUL3 1/20 0.33
FFAR1 O14842 1/20 0.33
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dihydrolipoic Acid SCHEMBL715539 0.85 NFKB1 (0.33) NFKB1
Dihydrolipoic Acid SCHEMBL867951 0.83 FOLH1 (0.56) GSTK1FOLH1ENPEPANPEPLMNA
Dihydrolipoic Acid SCHEMBL19773 0.83 FOLH1 (0.56) GSTK1FOLH1ENPEPANPEPLMNA
Dihydrolipoic Acid SCHEMBL1115003 0.83 FOLH1 (0.56) GSTK1FOLH1ENPEPANPEPLMNA
Dihydrolipoic Acid SCHEMBL618576 0.83 FOLH1 (0.56) GSTK1FOLH1ENPEPANPEPLMNA
Dihydrolipoic Acid SCHEMBL2578740 0.82 FOLH1 (0.54) GSTK1FOLH1ENPEPANPEPLMNA
Dihydrolipoic Acid SCHEMBL19359055 0.82 FOLH1 (0.54) GSTK1FOLH1ENPEPANPEPLMNA
SCHEMBL21611884 0.82 GSTK1 (0.57) GSTK1FOLH1ENPEPANPEPLMNA
SCHEMBL6809842 0.82 GSTK1 (0.57) GSTK1FOLH1ENPEPANPEPLMNA
SCHEMBL6805309 0.82 GSTK1 (0.57) GSTK1FOLH1ENPEPANPEPLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2575742-B1 IMPROVEMENTS IN OR RELATING TO DEPILATORY COMPOSITIONS RECKITT & COLMAN OVERSEAS (GB) 2016-11-02 EP claimed
EP-1824446-A2 NON-IRRITATING RAPID-ACTION DEPILATORY COMPOSITION Producciones Infovision (MX) 2007-08-29 EP disclosed
WO-2006048526-A2 NON-IRRITATING RAPID-ACTION DEPILATORY COMPOSITION PRODUCCIONES INFOVISION (MX) 2006-05-11 WO disclosed