Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14806780 | 0.86 | NPSR1 (0.45) | NPSR1KDM4EALDH1A1SMN1; SMN2MAOA | |
| SCHEMBL23444278 | 0.80 | NPSR1 (0.54) | NPSR1KDM4EALDH1A1SMN1; SMN2MAOA | |
| SCHEMBL21449885 | 0.80 | NPSR1 (0.50) | NPSR1KDM4EALDH1A1SMN1; SMN2MAOA | |
| SCHEMBL21852716 | 0.80 | NPSR1 (0.50) | NPSR1KDM4EALDH1A1SMN1; SMN2MAOA | |
| SCHEMBL12187917 | 0.79 | NPSR1 (0.58) | NPSR1KDM4EALDH1A1SMN1; SMN2MAOA | |
| SCHEMBL11865351 | 0.79 | ALDH1A1 (0.50) | NPSR1KDM4EALDH1A1SMN1; SMN2MAOA | |
| SCHEMBL11930015 | 0.79 | NPSR1 (0.46) | NPSR1KDM4EALDH1A1SMN1; SMN2MAOA | |
| SCHEMBL9217368 | 0.78 | NPSR1 (0.60) | NPSR1KDM4EALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL14560537 | 0.75 | NPSR1 (0.57) | NPSR1KDM4EALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL2474607 | 0.75 | TTR (0.55) | NPSR1KDM4EALDH1A1SMN1; SMN2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133551-A1 | HISTONE DEACETYLASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-06-30 | — | — | WO | disclosed |
| EP-3831824-A1 | PREPARATION AND APPLICATION OF CLASS OF N-CONTAINING HETEROCYCLIC COMPOUNDS HAVING IMMUNOREGULATORY FUNCTION | Shanghai Ennovabio Pharmaceuticals Co., Ltd. (CN) | 2021-06-09 | — | — | EP | disclosed |
| EP-2978820-B1 | WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES | NITTO DENKO CORP (JP) | 2018-03-21 | — | — | EP | disclosed |
| EP-2788450-B1 | WAVELENGTH CONVERSION MATERIAL AS ENCAPSULANT FOR SOLAR MODULE SYSTEMS TO ENHANCE SOLAR HARVESTING EFFICIENCY | NITTO DENKO CORP (JP) | 2017-06-21 | — | — | EP | disclosed |
| US-9399730-B2 | Wavelength conversion material as encapsulate for solar module systems to enhance solar harvesting efficiency | NITTO DENKO CORPORATION (JP) | 2016-07-26 | — | — | US | disclosed |
| US-9394479-B2 | Wavelength conversion film having pressure sensitive adhesive layer to enhance solar harvesting efficiency | NITTO DENKO CORPORATION (JP) | 2016-07-19 | — | — | US | disclosed |
| US-9382424-B2 | Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency | NITTO DENKO CORPORATION (JP) | 2016-07-05 | — | — | US | disclosed |
| US-20160108310-A1 | WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES | NITTO DENKO CORPORATION (JP) | 2016-04-21 | — | — | US | disclosed |
| US-20150041052-A1 | WAVELENGTH CONVERSION LAYER ON A GLASS PLATE TO ENHANCE SOLAR HARVESTING EFFICIENCY | NITTO DENKO CORPORATION (JP) | 2015-02-12 | — | — | US | disclosed |
| US-20150041042-A1 | PRESSURE SENSITIVE ADHESIVE TYPE OF WAVELENGTH CONVERSION TAPE FOR ENHANCING SOLAR HARVESTING EFFICIENCY | NITTO DENKO CORPORATION (JP) | 2015-02-12 | — | — | US | disclosed |
| US-RE38524-E1 | Dipeptide derivatives as growth hormone secretagogues | PFIZER INC. | 2004-06-01 | — | — | US | disclosed |
| US-20040009984-A1 | Increasing levels of endogenous growth hormone, especially treating osterporosis, aging frailty or congestive heart failure | CARPINO PHILIP ALBERT (US) | 2004-01-15 | — | — | US | disclosed |
| US-20040006063-A1 | Dipeptide derivatives | CARPINO PHILIP ALBERT (US) | 2004-01-08 | — | — | US | disclosed |
| US-20030216399-A1 | Dipeptide derivatives | CARPINO PHILIP ALBERT (US) | 2003-11-20 | — | — | US | disclosed |
| US-6525047-B2 | Which are growth hormone secretogogues and increase the level of endogenous growth hormone; treating osteoporosis, congestive heart failure, frailty associated with aging, obesity; accelerating bone fracture repair | PFIZER INC. | 2003-02-25 | — | — | US | disclosed |
| US-6433171-B1 | FOR OSTEOPOROSIS AND/OR FRAILTY, CONGESTIVE HEART FAILURE, FRAILTY ASSOCIATED WITH AGING, OBESITY; ACCELERATING BONE FRACTURE REPAIR, ATTENUATING PROTEIN CATABOLIC RESPONSE AFTER A MAJOR OPERATION, REDUCING CACHEXIA AND PROTEIN LOSS | PFIZER INC. | 2002-08-13 | — | — | US | disclosed |
| US-6432945-B1 | Dipeptide derivatives | PFIZER INC. | 2002-08-13 | — | — | US | disclosed |
| US-20020042415-A1 | Dipeptide derivatives | CARPINO PHILIP ALBERT (US) | 2002-04-11 | — | — | US | disclosed |
| US-20010041703-A1 | Dipeptide derivatives | CARPINO PHILIP ALBERT (US) | 2001-11-15 | — | — | US | disclosed |
| US-6251902-B1 | Dipeptide derivatives as growth hormone secretagogues | PFIZER INC. | 2001-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009984-A1 | Increasing levels of endogenous growth hormone, especially treating osterporosis, aging frailty or congestive heart failure | GHSR, GHRHR, GIPR | NPSR1 554/4885KDM4E 4543/4885ALDH1A1 3158/4885 |
| US-20020042415-A1 | Dipeptide derivatives | GIPR, GHRHR, GHSR | NPSR1 287/4885KDM4E 4596/4885ALDH1A1 3934/4885 |
| US-20010041703-A1 | Dipeptide derivatives | GIPR, GHRHR, GHSR | NPSR1 379/4885KDM4E 4540/4885ALDH1A1 3986/4885 |
| US-20040006063-A1 | Dipeptide derivatives | GIPR, GHRHR, GHSR | NPSR1 414/4885KDM4E 4247/4885ALDH1A1 3126/4885 |
| US-20030216399-A1 | Dipeptide derivatives | GIPR, GHRHR, GHSR | NPSR1 287/4885KDM4E 4596/4885ALDH1A1 3934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.