Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232161 | 0.99 | HTR6 (0.53) | HTR6L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL5231031 | 0.89 | HTR6 (0.57) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5226476 | 0.87 | HTR6 (0.51) | HTR6L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL5228765 | 0.86 | HTR6 (0.51) | HTR6L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL3596183 | 0.79 | HTR6 (0.69) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL3591828 | 0.78 | HTR6 (0.67) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5227156 | 0.76 | HTR6 (0.48) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL28245177 | 0.75 | HTR6 (0.64) | HTR6 | |
| SCHEMBL27636794 | 0.73 | HTR6 (0.65) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5262967 | 0.72 | HTR6 (0.49) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1523486-B1 | TETRACYCLIC ARYLSULFONYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY | SUVEN LIFE SCIENCES LTD (IN) | 2007-11-07 | — | — | EP | disclosed |