Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28245177 | 0.78 | HTR6 (0.64) | HTR6 | |
| SCHEMBL5330866 | 0.76 | HTR6 (0.50) | HTR6KLK7 | |
| SCHEMBL3600967 | 0.76 | HTR6 (0.62) | HTR6 | |
| SCHEMBL27636794 | 0.74 | HTR6 (0.65) | HTR6 | |
| SCHEMBL5227430 | 0.72 | HTR6 (0.53) | HTR6 | |
| SCHEMBL947647 | 0.71 | HTR6 (0.74) | HTR6 | |
| SCHEMBL5232161 | 0.71 | HTR6 (0.53) | HTR6 | |
| SCHEMBL3587283 | 0.71 | HTR6 (0.72) | HTR6 | |
| SCHEMBL5228788 | 0.70 | HTR6 (0.51) | HTR6KLK7 | |
| SCHEMBL27636875 | 0.70 | HTR6 (0.57) | HTR6FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1523486-B1 | TETRACYCLIC ARYLSULFONYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY | SUVEN LIFE SCIENCES LTD (IN) | 2007-11-07 | — | — | EP | disclosed |