Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 14/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1994568 | 0.90 | OPRD1 (0.63) | OPRD1OPRK1OPRM1KCNH2 | |
| SCHEMBL6242273 | 0.87 | OPRD1 (0.57) | OPRD1OPRK1OPRM1KCNH2 | |
| SCHEMBL1999193 | 0.87 | OPRD1 (0.58) | OPRD1OPRK1OPRM1KCNH2 | |
| SCHEMBL1999941 | 0.87 | OPRD1 (0.58) | OPRD1OPRK1OPRM1KCNH2 | |
| Hydrochloric Acid SCHEMBL6260845 | 0.86 | OPRD1 (0.56) | OPRD1OPRK1OPRM1KCNH2 | |
| SCHEMBL1142992 | 0.86 | OPRD1 (0.56) | OPRD1OPRK1OPRM1KCNH2 | |
| SCHEMBL1999513 | 0.86 | OPRD1 (0.55) | OPRD1OPRK1OPRM1KCNH2 | |
| SCHEMBL1999813 | 0.85 | OPRD1 (0.64) | OPRD1OPRK1OPRM1KCNH2 | |
| SCHEMBL2004774 | 0.84 | OPRD1 (0.52) | OPRD1OPRK1OPRM1KCNH2 | |
| SCHEMBL2004772 | 0.84 | OPRD1 (0.52) | OPRD1OPRK1OPRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254890-A1 | 4(Phenyl-Piperazinyl-Methyl) Benzamide Derivatives and Their Use for the Treatment of Pain or Gastrointestinal Disorders | ASTRAZENECA AB (SE) | 2007-11-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254890-A1 | 4(Phenyl-Piperazinyl-Methyl) Benzamide Derivatives and Their Use for the Treatment of Pain or Gastrointestinal Disorders | TRPV1, OPRM1, OPRK1 | OPRD1 6/4885OPRK1 3/4885OPRM1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.