Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226513 | 0.88 | RAB9A (0.46) | RAB9ASMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL5184418 | 0.87 | KDR (0.59) | RAB9ASMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL5231291 | 0.85 | PABPC1 (0.58) | RAB9ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL5184813 | 0.82 | NPSR1 (0.49) | RAB9ASMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL13991492 | 0.81 | HDAC1 (0.72) | RAB9ASMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL15477454 | 0.79 | HDAC1 (0.59) | RAB9ASMN1; SMN2KDM4EMAPTKDR | |
| SCHEMBL13991493 | 0.79 | HDAC1 (0.77) | RAB9ASMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL29433000 | 0.79 | RAB9A (0.73) | RAB9ASMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL5185017 | 0.78 | RAB9A (0.46) | RAB9ASMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL28188767 | 0.78 | HDAC1 (0.67) | RAB9ASMN1; SMN2KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758920-A1 | BACTERIAL EFFLUX PUMP INHIBITORS AND METHODS OF TREATING BACTERIAL INFECTIONS | MPEX PHARMACEUTICALS, INC. (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005113579-A1 | BACTERIAL EFFLUX PUMP INHIBITORS AND METHODS OF TREATING BACTERIAL INFECTIONS | MPEX PHARMACEUTICALS, INC. (US) | 2005-12-01 | — | — | WO | disclosed |