Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227510 | 0.88 | RAB9A (0.58) | RAB9AKDM4ESMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4950199 | 0.83 | KDR (0.39) | RAB9AKDM4EMAPTALDH1A1TRPV1 | |
| SCHEMBL5231291 | 0.79 | PABPC1 (0.58) | RAB9ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL4950201 | 0.78 | ROCK2 (0.46) | RAB9AKDM4ESMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5185017 | 0.77 | RAB9A (0.46) | RAB9AKDM4ESMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL22410706 | 0.76 | KDR (0.50) | RAB9AKDM4ESMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5184418 | 0.76 | KDR (0.59) | RAB9AKDM4ESMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4952954 | 0.75 | NPC1 (0.44) | RAB9AKDM4ESMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4950391 | 0.72 | PLAU (0.52) | RAB9AKDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL4952020 | 0.72 | CNR1 (0.41) | TRPV1KDRHDAC4CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758920-A1 | BACTERIAL EFFLUX PUMP INHIBITORS AND METHODS OF TREATING BACTERIAL INFECTIONS | MPEX PHARMACEUTICALS, INC. (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005113579-A1 | BACTERIAL EFFLUX PUMP INHIBITORS AND METHODS OF TREATING BACTERIAL INFECTIONS | MPEX PHARMACEUTICALS, INC. (US) | 2005-12-01 | — | — | WO | disclosed |