Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.65 |
| ▸ | KDR | P35968 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226515 | 0.88 | ACP1 (0.51) | ACP1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL5231297 | 0.85 | PABPC1 (0.58) | ACP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5184940 | 0.85 | ACP1 (0.62) | ACP1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL5184424 | 0.83 | ACP1 (0.69) | ACP1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL5183680 | 0.80 | ACP1 (0.67) | ACP1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL18289710 | 0.79 | ACP1 (1.00) | ACP1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL5185024 | 0.78 | ACP1 (0.53) | ACP1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL27599000 | 0.77 | HDAC1 (0.67) | KDRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL651159 | 0.76 | KDR (0.74) | ACP1KDRHDAC3HDAC4HDAC1 | |
| SCHEMBL30858817 | 0.76 | ACP1 (0.59) | ACP1KDRHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758920-A1 | BACTERIAL EFFLUX PUMP INHIBITORS AND METHODS OF TREATING BACTERIAL INFECTIONS | MPEX PHARMACEUTICALS, INC. (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005113579-A1 | BACTERIAL EFFLUX PUMP INHIBITORS AND METHODS OF TREATING BACTERIAL INFECTIONS | MPEX PHARMACEUTICALS, INC. (US) | 2005-12-01 | — | — | WO | disclosed |