Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 10/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11571903 | 0.80 | BCHE (0.66) | BCHEKMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL5228081 | 0.78 | BCHE (0.68) | BCHEKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL5947311 | 0.78 | BCHE (0.64) | BCHEKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL30877044 | 0.77 | MAPK1 (0.77) | BCHEKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL27312115 | 0.77 | MAPK1 (0.77) | BCHEKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL31614388 | 0.77 | BCHE (0.57) | BCHEKMT2AALDH1A1MEN1MPO | |
| SCHEMBL11714815 | 0.77 | BCHE (0.57) | BCHEKMT2AALDH1A1MEN1MPO | |
| SCHEMBL4859974 | 0.76 | BCHE (0.77) | BCHEKMT2AALDH1A1LMNAMPO | |
| SCHEMBL22864059 | 0.75 | L3MBTL1 (0.46) | KMT2AALDH1A1MEN1LMNASMN1; SMN2 | |
| SCHEMBL21243275 | 0.75 | ALDH1A1 (0.58) | BCHEKMT2AALDH1A1MEN1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379239-B1 | N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | LILLY CO ELI (US) | 2007-09-12 | — | — | EP | claimed |
| EP-1379239-B1 | N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | LILLY CO ELI (US) | 2007-09-12 | — | — | EP | disclosed |