Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 9/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5947311 | 0.91 | BCHE (0.64) | BCHEKMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL5223504 | 0.84 | BCHE (0.66) | BCHESMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5947382 | 0.83 | BCHE (0.77) | BCHEKMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL5222217 | 0.81 | BCHE (0.66) | BCHEKMT2ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL21243275 | 0.80 | ALDH1A1 (0.58) | BCHEKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL9080552 | 0.79 | ALDH1A1 (0.76) | BCHEKMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL5228083 | 0.78 | BCHE (0.56) | BCHEKMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL5947547 | 0.78 | BCHE (0.59) | BCHESMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5947412 | 0.78 | KDM4E (0.79) | BCHEKMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL2533896 | 0.77 | BCHE (0.57) | BCHESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379239-B1 | N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | LILLY CO ELI (US) | 2007-09-12 | — | — | EP | claimed |
| EP-1379239-B1 | N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | LILLY CO ELI (US) | 2007-09-12 | — | — | EP | disclosed |