Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 2/20 | 0.47 |
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761123 | 0.90 | SMO (0.50) | SMOMAP4K1DRD4MAPTL3MBTL1 | |
| SCHEMBL5737789 | 0.88 | SMO (0.44) | SMODRD4DRD3DRD2MAPK14 | |
| SCHEMBL5228124 | 0.83 | SMO (0.43) | SMODRD4DRD3DRD2MAPK14 | |
| SCHEMBL5230174 | 0.83 | DRD4 (0.46) | SMODRD4DRD3DRD2MAPK14 | |
| SCHEMBL1689504 | 0.83 | SMO (0.45) | SMOMAP4K1DRD4DRD3DRD2 | |
| SCHEMBL5224153 | 0.83 | BRD4 (0.44) | SMODRD4DRD3DRD2MAPT | |
| SCHEMBL2761009 | 0.82 | SMO (0.43) | SMODRD4DRD3DRD2MAPK14 | |
| SCHEMBL5226797 | 0.82 | SMO (0.61) | SMOMAPK14MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL2761085 | 0.82 | DHODH (0.43) | SMOMAP4K1DRD4DRD3DRD2 | |
| SCHEMBL5226795 | 0.82 | SMO (0.42) | SMODRD4DRD3DRD2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611122-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-06-13 | — | — | EP | disclosed |