Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4813045 | 0.90 | ALDH1A1 (0.45) | LMNAALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL4810454 | 0.88 | EGLN2 (0.41) | LMNAALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL4819308 | 0.86 | TP53 (0.42) | LMNAALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL4819279 | 0.86 | EGLN2 (0.40) | LMNAALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL4821684 | 0.86 | ALDH1A1 (0.47) | LMNAALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL8917364 | 0.86 | LMNA (0.44) | LMNAALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL15341363 | 0.86 | LMNA (0.43) | LMNAALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL4821793 | 0.85 | TSHR (0.45) | LMNAALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL4929317 | 0.84 | LMNA (0.44) | LMNAALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL4820371 | 0.84 | TSHR (0.48) | LMNAALDH1A1MAPTTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307172-B2 | 7-amino triazolopyrimidines for controlling harmful fungi | BASF AKTIENGESELLSCHAFT (DE) | 2007-12-11 | — | — | US | claimed |
| EP-1414302-B1 | 7-AMINO TRIAZOLOPYRIMIDINES FOR CONTROLLING HARMFUL FUNGI | BASF AG (DE) | 2007-03-21 | — | — | EP | claimed |