SCHEMBL8917364

SCHEMBL8917364

CC1CCN(c2c(-c3ccccc3Cl)c(Cl)nc3ncnn23)CC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.44
ALDH1A1 P00352 5/20 0.44
TSHR P16473 3/20 0.44
MAPT P10636 1/20 0.44
NPSR1 Q6W5P4 3/20 0.43
KDM4E B2RXH2 1/20 0.43
NPC1 O15118 1/20 0.43
STAT6 P42226 1/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
GLA P06280 1/20 0.41
PDE2A O00408 6/20 0.41
HSD11B1 P28845 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
EGLN2 Q96KS0 2/20 0.37
MEN1 O00255 1/20 0.37
USP2 O75604 1/20 0.37
TP53 P04637 1/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8390059 0.90 LMNA (0.45) LMNAALDH1A1TSHRMAPTNPSR1
SCHEMBL4819333 0.89 PDE2A (0.39) LMNAALDH1A1TSHRMAPTNPSR1
SCHEMBL15341363 0.88 LMNA (0.43) LMNAALDH1A1TSHRMAPTNPSR1
SCHEMBL5228613 0.86 LMNA (0.48) LMNAALDH1A1TSHRMAPTNPSR1
SCHEMBL8916382 0.86 LMNA (0.41) LMNAALDH1A1TSHRMAPTNPSR1
SCHEMBL3424653 0.85 PDE2A (0.45) LMNAALDH1A1TSHRMAPTNPSR1
SCHEMBL4819318 0.84 PDE2A (0.43) LMNAALDH1A1TSHRMAPTNPSR1
SCHEMBL344327 0.84 TSHR (0.46) LMNAALDH1A1TSHRMAPTNPSR1
SCHEMBL8919073 0.83 PDE2A (0.41) LMNAALDH1A1TSHRMAPTNPSR1
SCHEMBL8486163 0.82 ALDH1A1 (0.43) LMNAALDH1A1TSHRMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5593996-A FUNGICIDES AMERICAN CYANAMID COMPANY (US) 1997-01-14 US disclosed