Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 6/20 | 0.55 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495766 | 0.98 | CA2 (0.58) | CA2CASP1PPARAPPARGMMP13 | |
| SCHEMBL7495758 | 0.98 | CA2 (0.58) | CA2CASP1PPARAPPARGMMP13 | |
| SCHEMBL5227527 | 0.98 | CA2 (0.58) | CA2CASP1PPARAPPARGMMP13 | |
| SCHEMBL5230909 | 0.86 | CASP1 (0.52) | CA2CASP1PPARAPPARGMMP13 | |
| SCHEMBL1541597 | 0.85 | CASP1 (0.62) | CA2CASP1PPARAPPARGMMP13 | |
| SCHEMBL4973400 | 0.85 | CASP1 (0.62) | CA2CASP1PPARAPPARGMMP13 | |
| SCHEMBL6487973 | 0.85 | CASP1 (0.62) | CA2CASP1PPARAPPARGMMP13 | |
| SCHEMBL7492863 | 0.84 | MTNR1A (0.45) | CA2CASP1 | |
| SCHEMBL7493194 | 0.84 | MTNR1A (0.45) | CA2CASP1 | |
| SCHEMBL7492869 | 0.84 | MTNR1A (0.45) | CA2CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340744-B1 | Hiv protease inhibitors | AGOURON PHARMA (US) | 2007-05-23 | — | — | EP | disclosed |
| EP-0889036-B1 | HIV protease inhibitors | AGOURON PHARMA (US) | 2004-12-29 | — | — | EP | disclosed |
| US-6693199-B2 | DEPROTECTING CARBAMATE GROUP AND AMIDATING IN PRESENCE OF SUCH AS HYDROXYBENZOTRIAZOLE HYDRATE PROMOTER | AGOURON PHARMACEUTICALS, INC. | 2004-02-17 | — | — | US | disclosed |
| EP-1340744-A2 | Hiv protease inhibitors | Agouron Pharmaceuticals, Inc. (US) | 2003-09-03 | — | — | EP | disclosed |
| EP-0722439-B1 | HIV PROTEASE INHIBITORS | AGOURON PHARMA (US) | 2002-08-14 | — | — | EP | disclosed |
| US-6271235-B1 | VIRICIDE | AGOURON PHARMACEUTICALS, INC. | 2001-08-07 | — | — | US | disclosed |
| US-6162812-A | Pharmaceutical compositions containing HIV protease inhibitors and methods of their use | AGOURON PHARMACEUTICALS, INC. (US) | 2000-12-19 | — | — | US | disclosed |
| EP-0763017-B1 | N-(3-AMINO-2-HYDROXYBUTYL)SULPHONAMIDE DERIVATIVES AS HIV PROTEASE INHIBITORS | AGOURON PHARMA (US) | 2000-09-13 | — | — | EP | disclosed |
| US-5952343-A | VIRICIDES; SPECIFICITY; NONTOXIC | AGOURON PHARMACEUTICALS, INC. | 1999-09-14 | — | — | US | disclosed |
| EP-0889036-A1 | HIV protease inhibitors | AGOURON PHARMACEUTICALS, INC. (US) | 1999-01-07 | — | — | EP | disclosed |
| US-5852043-A | HIV protease inhibitors | AGOURON PHARMACEUTICALS, INC. | 1998-12-22 | — | — | US | disclosed |
| US-5846993-A | HIV protease inhibitors | AGOURON PHARMACEUTICALS, INC. | 1998-12-08 | — | — | US | disclosed |
| US-5837710-A | HIV protease inhibitors | AGOURON PHARMACEUTICALS, INC. | 1998-11-17 | — | — | US | disclosed |
| US-5834467-A | AIDS TREATMENT; VIRICIDES | AGOURON PHARMACEUTICALS, INC. | 1998-11-10 | — | — | US | disclosed |
| US-5827859-A | ADMINISTERED TO TREAT AIDS; VIRICIDES | AGOURON PHARMACEUTICALS, INC. | 1998-10-27 | — | — | US | disclosed |
| US-5827891-A | FOR TREATMENT OF AIDS, BLOCKING REPLICATION OF HIV VIRUS | AGOURON PHARMACEUTICALS, INC. | 1998-10-27 | — | — | US | disclosed |
| US-5827858-A | ADMINISTERED TO TREAT AIDS | AGOURON PHARMACEUTICALS, INC. | 1998-10-27 | — | — | US | disclosed |
| US-5824688-A | HIV protease inhibitors | AGOURON PHARMACEUTICALS, INC. | 1998-10-20 | — | — | US | disclosed |
| US-5527829-A | VIRICIDES; TREATING AIDS | AGOURON PHARMACEUTICALS, INC. (US) | 1996-06-18 | — | — | US | disclosed |
| US-5484926-A | VIRICIDES AND ENZYME INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 1996-01-16 | — | — | US | disclosed |