Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4807994 | 0.94 | NPC1 (0.31) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL5318571 | 0.92 | NPC1 (0.32) | NPC1RAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4805175 | 0.82 | NPC1 (0.34) | NPC1RAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5225697 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL5215835 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL4804209 | 0.76 | RAB9A (0.34) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL5196641 | 0.75 | RAB9A (0.34) | NPC1RAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4802401 | 0.72 | — | — | |
| SCHEMBL5196304 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL4806006 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1548006-B1 | Synthesis of tetraazapentamethine derivatives, keratin fibers dyeing process which uses such synthesis | OREAL (FR) | 2007-09-05 | — | — | EP | claimed |