Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 13/20 | 0.41 |
| ▸ | CDK2 | P24941 | 13/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE6D | O43924 | 1/20 | 0.37 |
| ▸ | PDE8A | O60658 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486289 | 0.75 | KDM4E (0.41) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL8148622 | 0.73 | PDE4A (0.32) | PDE3BPDE3APDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL5231288 | 0.72 | ADORA2B (0.49) | CCNE1CDK2CCNE2CCNT1CDK1 | |
| SCHEMBL21617342 | 0.69 | PDE3B (0.58) | CCNE1CDK2CCNE2PDE3BPDE3A | |
| SCHEMBL8483161 | 0.68 | ADORA2A (0.32) | PDE3APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2643830 | 0.67 | XDH (0.41) | CCNE1CDK2CCNE2CCNT1CDK1 | |
| SCHEMBL12241751 | 0.67 | PDE3B (0.44) | CCNE1CDK2CCNE2CCNT1CDK1 | |
| 1-Methylxanthine SCHEMBL12037451 | 0.67 | ADORA2A (0.54) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9240979 | 0.63 | ADORA2A (0.58) | PDE3APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20195380 | 0.63 | PDE3B (0.41) | CCNE1CDK2CCNE2CCNT1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092435-B1 | REMEDIES FOR DIABETES | KYOWA HAKKO KOGYO KK (JP) | 2007-04-04 | — | — | EP | disclosed |