SCHEMBL5229338

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10652117	0.78	CCR1 (0.39)	CCR1PGRALOX5CES2CES1
	SCHEMBL988253	0.77	TSHR (0.48)	CCR1TSHRKMT2AHTTALDH1A1
	SCHEMBL28981574	0.77	TRPA1 (0.35)	CCR1TSHRKMT2ANPC1RAB9A
	SCHEMBL9521376	0.76	FFAR1 (0.45)	CCR1ALOX5TSHRCES2CES1
	SCHEMBL28611237	0.74	CTSC (0.42)	CCR1KMT2AALDH1A1ESR1ESR2
	SCHEMBL3229012	0.73	NPC1 (0.53)	ALOX5TSHRCES2CES1KEAP1
	SCHEMBL14525329	0.73	NPC1 (0.53)	ALOX5TSHRCES2CES1KEAP1
	SCHEMBL164851	0.73	SLC6A2 (0.41)	ALOX5KMT2AHTTNPSR1SLC6A2
	SCHEMBL2563122	0.73	SLC6A2 (0.41)	ALOX5KMT2AHTTNPSR1SLC6A2
	SCHEMBL9177248	0.72	CCR1 (0.37)	CCR1PGRALOX5TSHRCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.