Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | LMNA | P02545 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5229206 | 0.87 | F2 (0.39) | ALDH1A1LMNANPC1RAB9AHTT | |
| SCHEMBL5236615 | 0.84 | F10 (0.37) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL5237059 | 0.83 | MAPT (0.37) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL4884938 | 0.83 | F10 (0.42) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL8256288 | 0.81 | F10 (0.44) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL8258622 | 0.81 | F10 (0.44) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL5242014 | 0.81 | NPC1 (0.35) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL4886660 | 0.78 | ROCK2 (0.30) | — | |
| SCHEMBL5231707 | 0.76 | SIRT2 (0.34) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL4634074 | 0.76 | GCGR (0.38) | ALDH1A1MAPTNPC1RAB9AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819701-A1 | CYCLIC IMINOCARBAMATES AND USE THEREOF | Bayer HealthCare AG (DE) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006058630-A1 | CYCLIC IMINOCARBAMATES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-06-08 | — | — | WO | disclosed |