Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | HSPD1 | P10809 | 4/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.51 |
| ▸ | HSPE1 | P61604 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233621 | 0.88 | SMN1; SMN2 (0.53) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL12334078 | 0.86 | RORA (0.62) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL7573917 | 0.83 | MAPT (0.64) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL5231184 | 0.82 | MAPT (0.68) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL5231919 | 0.82 | MEN1 (0.60) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL7569591 | 0.80 | MAPT (0.68) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL29118849 | 0.80 | MAPT (0.64) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL7573063 | 0.79 | MAPT (0.63) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL5228685 | 0.78 | MEN1 (0.56) | MEN1KMT2AMAPTCA1CA2 | |
| SCHEMBL5229776 | 0.77 | MEN1 (0.55) | MEN1KMT2AMAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519932-B1 | BISARYLSULFONAMIDE COMPOUNDS AND THEIR USE IN CANCER THERAPY | CYCLACEL LTD (GB) | 2007-10-03 | — | — | EP | claimed |