Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 14/20 | 1.00 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.52 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2942439 | 0.83 | MLYCD (1.00) | MLYCDNR1H2NR1H3 | |
| SCHEMBL5231602 | 0.80 | MLYCD (0.69) | MLYCDRORC | |
| SCHEMBL24279551 | 0.79 | MLYCD (0.65) | MLYCD | |
| SCHEMBL10681264 | 0.75 | MLYCD (0.60) | MLYCD | |
| SCHEMBL5231374 | 0.74 | MLYCD (1.00) | MLYCDNR1H3RORC | |
| SCHEMBL2080809 | 0.72 | MLYCD (0.69) | MLYCDNR1H2NR1H3 | |
| SCHEMBL24279554 | 0.72 | MLYCD (0.56) | MLYCD | |
| SCHEMBL6493549 | 0.71 | MLYCD (0.63) | MLYCDNR1H2NR1H3 | |
| SCHEMBL14732184 | 0.69 | RORC (0.77) | NR1H2NR1H3RORC | |
| SCHEMBL6496268 | 0.69 | NR1H2 (0.63) | MLYCDNR1H2NR1H3RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353662-B1 | METHODS FOR THE TREATMENT OF DISEASES USING MALONYL-COA DECARBOX YLASE INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2007-04-18 | — | — | EP | claimed |