Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 17/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843613 | 0.87 | MLYCD (0.71) | MLYCDLMNARORCSMN1; SMN2 | |
| SCHEMBL5231374 | 0.82 | MLYCD (1.00) | MLYCDLMNARORCSMN1; SMN2 | |
| SCHEMBL5229710 | 0.80 | MLYCD (1.00) | MLYCDRORC | |
| SCHEMBL6493549 | 0.79 | MLYCD (0.63) | MLYCDLMNASMN1; SMN2 | |
| SCHEMBL6470863 | 0.77 | ESR1 (0.41) | MLYCD | |
| SCHEMBL6470937 | 0.76 | ALDH1A1 (0.55) | SMN1; SMN2 | |
| SCHEMBL11472535 | 0.74 | MLYCD (0.66) | MLYCDLMNASMN1; SMN2 | |
| SCHEMBL6496268 | 0.74 | NR1H2 (0.63) | MLYCDLMNARORCSMN1; SMN2 | |
| SCHEMBL3221857 | 0.73 | MLYCD (0.69) | MLYCDLMNA | |
| SCHEMBL6843778 | 0.73 | MLYCD (0.64) | MLYCDLMNARORCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353662-B1 | METHODS FOR THE TREATMENT OF DISEASES USING MALONYL-COA DECARBOX YLASE INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2007-04-18 | — | — | EP | claimed |