Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 9/20 | 1.00 |
| ▸ | CDK4 | P11802 | 3/20 | 1.00 |
| ▸ | CCND1 | P24385 | 3/20 | 1.00 |
| ▸ | CDK2 | P24941 | 3/20 | 1.00 |
| ▸ | PRKCA | P17252 | 3/20 | 1.00 |
| ▸ | CCNE2 | O96020 | 2/20 | 1.00 |
| ▸ | PRKACA | P17612 | 2/20 | 1.00 |
| ▸ | PRKACG | P22612 | 2/20 | 1.00 |
| ▸ | PRKACB | P22694 | 2/20 | 1.00 |
| ▸ | CCNE1 | P24864 | 2/20 | 1.00 |
| ▸ | CAMK2D | Q13557 | 2/20 | 1.00 |
| ▸ | ABL1 | P00519 | 2/20 | 1.00 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 1/20 | 1.00 |
| ▸ | CCNB2 | O95067 | 1/20 | 1.00 |
| ▸ | PRKCG | P05129 | 1/20 | 1.00 |
| ▸ | CDK1 | P06493 | 1/20 | 1.00 |
| ▸ | PIM1 | P11309 | 1/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 1/20 | 1.00 |
| ▸ | PRKCH | P24723 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ro-316233 SCHEMBL29373011 | 1.00 | PRKCB (1.00) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL3148490 | 0.92 | PRKCB (0.84) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL13917970 | 0.88 | PRKCB (0.78) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL3908534 | 0.88 | PRKCB (0.78) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL29756414 | 0.88 | PRKCB (0.78) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL5333315 | 0.88 | PRKCB (0.78) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL8167180 | 0.88 | PRKCB (0.78) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL6098588 | 0.88 | PRKCB (0.78) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL6823304 | 0.88 | PRKCB (0.78) | PRKCBCDK4CCND1CDK2PRKCA | |
| SCHEMBL9085236 | 0.86 | PRKCB (0.74) | PRKCBCDK4CCND1CDK2PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120044159-A | Polygonatum sibiricum medicinal material species identification method based on polygonatum sibiricum characteristic compound and application | 河北北方学院 | 2025-05-27 | — | — | CN | claimed |
| US-20230201173-A1 | SMAD4 Complex Inducers and Uses in Cancer Therapy | UNIV EMORY (US) | 2023-06-29 | — | — | US | claimed |
| US-7129250-B2 | Neuroprotective and anti-proliferative compounds | AEGERA THERAPEUTICS INC. (CA) | 2006-10-31 | — | — | US | claimed |
| US-20060099568-A1 | Signals and molecular species involved in senescence | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2006-05-11 | — | — | US | claimed |
| WO-2004083202-A1 | A PROCESS FOR THE PREPARATION OF INDOLYMALEIMIDES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-09-30 | — | — | WO | claimed |
| US-20040102467-A1 | Neuroprotective and anti-proliferative compounds | AEGERA THERAPEUTICS INC. (CA) | 2004-05-27 | — | — | US | claimed |
| EP-0397060-B1 | Maleinimide derivatives and their use as medicines | GOEDECKE AG (DE) | 2001-11-21 | — | — | EP | claimed |
| EP-0397060-A2 | Maleinimide derivatives and their use as medicines | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-11-14 | — | — | EP | claimed |
| CN-120044159-A | Polygonatum sibiricum medicinal material species identification method based on polygonatum sibiricum characteristic compound and application | 河北北方学院 | 2025-05-27 | — | — | CN | disclosed |
| US-20230285556-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | OMEROS CORPORATION | 2023-09-14 | — | — | US | disclosed |
| US-20230201173-A1 | SMAD4 Complex Inducers and Uses in Cancer Therapy | UNIV EMORY (US) | 2023-06-29 | — | — | US | disclosed |
| EP-2211901-B2 | VACCINATION WITH MULTIPLE CLADES OF H5 INFLUENZA A VIRUS | SEQIRUS UK LTD (GB) | 2023-04-26 | — | — | EP | disclosed |
| US-20230094365-A1 | PIM KINASE INHIBITOR COMPOSITIONS, METHODS, AND USES THEREOF | SNAP BIO, INC. | 2023-03-30 | — | — | US | disclosed |
| US-20230002784-A1 | COMPOSITIONS AND METHODS FOR MODIFYING EUKARYOTIC CELLS | ORCHARD THERAPEUTICS (EUROPE) LIMITED (GB) | 2023-01-05 | — | — | US | disclosed |
| EP-0328026-B1 | SUBSTITUTED PYRROLES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-28 | — | — | EP | disclosed |
| EP-0397060-A3 | MALEINIMIDE DERIVATIVES AND THEIR USE AS MEDICINES | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-5057614-A | Antiinflammatory, immunology, bronchodilator agents, cardiovascular disorders | HOFFMANN-LA ROCHE INC. (US) | 1991-10-15 | — | — | US | disclosed |
| EP-0397060-A2 | Maleinimide derivatives and their use as medicines | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-11-14 | — | — | EP | disclosed |
| EP-0397060-A2 | Maleinimide derivatives and their use as medicines | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-11-14 | — | — | EP | disclosed |
| EP-0328026-A1 | Substituted pyrroles | F. HOFFMANN-LA ROCHE AG (CH) | 1989-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230094365-A1 | PIM KINASE INHIBITOR COMPOSITIONS, METHODS, AND USES THEREOF | PIM1, PIM3, PIM2 | PRKCB 32/4885CDK4 198/4885CCND1 2406/4885 |
| US-20230285556-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | TP53, CD4, MCL1 | PRKCB 1254/4885CDK4 904/4885CCND1 1166/4885 |
| US-20040102467-A1 | Neuroprotective and anti-proliferative compounds | MKI67, NLN, BDNF | PRKCB 1519/4885CDK4 50/4885CCND1 92/4885 |
| US-20230002784-A1 | COMPOSITIONS AND METHODS FOR MODIFYING EUKARYOTIC CELLS | PHAX, CD4, POLM | PRKCB 2881/4885CDK4 3915/4885CCND1 2966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.