Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | AURKA | O14965 | 2/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231022 | 0.89 | RAB9A (0.43) | RAB9ANPC1AURKARPS6KB1AURKB | |
| SCHEMBL6479836 | 0.87 | ALDH1A1 (0.54) | RAB9ANPC1AURKARPS6KB1AURKB | |
| SCHEMBL940193 | 0.86 | RAB9A (0.44) | RAB9ANPC1AURKARPS6KB1AURKB | |
| SCHEMBL940614 | 0.80 | ALDH1A1 (0.44) | RAB9ANPC1AURKARPS6KB1AURKB | |
| SCHEMBL940713 | 0.79 | RAB9A (0.43) | RAB9ANPC1AURKARPS6KB1AURKB | |
| SCHEMBL6487647 | 0.77 | MEN1 (0.54) | RAB9ANPC1PTGS2ALDH1A1MAPT | |
| SCHEMBL940779 | 0.76 | MAPK1 (0.45) | RAB9ANPC1ALDH1A1MAPTADORA1 | |
| SCHEMBL6480798 | 0.73 | ALDH1A1 (0.48) | RAB9ANPC1ALDH1A1MAPTALOX12 | |
| SCHEMBL6489855 | 0.72 | ADORA3 (0.49) | RAB9ANPC1AURKAAURKBALDH1A1 | |
| SCHEMBL6479650 | 0.71 | MEN1 (0.54) | RAB9ANPC1ALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663982-B1 | AMINOQUINOLINE DERIVATIVES AND THEIR USE AS ADENOSINE A3 LIGANDS | SANOFI AVENTIS (FR) | 2007-11-21 | — | — | EP | claimed |