Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | HTR3A | P46098 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227450 | 0.90 | HRH3 (0.42) | HTR1AHTR2AHTR7HTR2BHTR6 | |
| SCHEMBL5230614 | 0.90 | ACHE (0.51) | HTR1AHTR2AHTR7HTR2BHTR6 | |
| SCHEMBL5227779 | 0.89 | ACHE (0.52) | HTR1AHTR2AHTR7HTR2BHTR6 | |
| SCHEMBL5226913 | 0.86 | HRH3 (0.45) | HTR1AHTR2AHTR7HTR2BHTR6 | |
| SCHEMBL5229632 | 0.85 | HTR2A (0.40) | HTR1AHTR2AHTR7HTR2BHTR6 | |
| SCHEMBL5228222 | 0.84 | HRH3 (0.39) | HTR1AHTR2AHTR7HTR2BHTR6 | |
| SCHEMBL5228031 | 0.83 | MAPK1 (0.40) | HTR1AHTR2AHTR7HTR2BHTR6 | |
| SCHEMBL2761010 | 0.79 | MAPT (0.41) | HTR1AHTR2AHTR7HTR2BHTR6 | |
| SCHEMBL2761086 | 0.79 | HTR2B (0.39) | HTR1AHTR2AHTR7HTR2BHTR6 | |
| SCHEMBL1997982 | 0.79 | ACHE (0.43) | HTR1AHTR2AHTR2BHTR2CHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611122-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-06-13 | — | — | EP | disclosed |