Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230180 | 0.86 | HTR1A (0.42) | HRH3TSHRALDH1A1HTR1AHTR2A | |
| SCHEMBL5230614 | 0.85 | ACHE (0.51) | HRH3HTR1AHTR2AHTR7HTR2B | |
| SCHEMBL5227779 | 0.85 | ACHE (0.52) | HRH3CNR1CNR2HTR1AHTR2A | |
| SCHEMBL5227450 | 0.84 | HRH3 (0.42) | HRH3ALDH1A1NPSR1HTR1AHTR2A | |
| SCHEMBL5228031 | 0.83 | MAPK1 (0.40) | CNR1CNR2HTR1AHTR2AHTR7 | |
| SCHEMBL2761178 | 0.81 | TSHR (0.48) | HRH3TSHRALDH1A1NPSR1CCR5 | |
| SCHEMBL5229632 | 0.79 | HTR2A (0.40) | HTR1AHTR2AHTR7HTR2BHTR3A | |
| SCHEMBL5907344 | 0.72 | MAPK1 (0.41) | HRH3CNR1CNR2HTR1AHTR2A | |
| SCHEMBL2761079 | 0.71 | TSHR (0.40) | HRH3TSHRALDH1A1NPSR1CCR5 | |
| SCHEMBL5226495 | 0.70 | NPSR1 (0.44) | HRH3TSHRALDH1A1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611122-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-06-13 | — | — | EP | disclosed |