Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231052 | 0.90 | PSEN1 (0.35) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27581944 | 0.90 | PSEN1 (0.34) | LMNACYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL5233891 | 0.89 | RORA (0.37) | DPP4SLC6A5PSEN1PSEN2APH1B | |
| SCHEMBL5275963 | 0.89 | RORA (0.37) | LMNACYP1A2CYP2C9TSHRSLC6A5 | |
| SCHEMBL5234034 | 0.89 | NPC1 (0.43) | DPP4LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL5238707 | 0.88 | LMNA (0.39) | DPP4LMNATHRATHRBALDH1A1 | |
| SCHEMBL5231641 | 0.88 | HTT (0.36) | LMNATSHRPSEN1PSEN2APH1B | |
| SCHEMBL5236407 | 0.88 | PGR (0.41) | DPP4SLC6A5KDM4EMEN1MAPT | |
| SCHEMBL5232809 | 0.88 | PTGDR2 (0.36) | KDM4EMAPT | |
| SCHEMBL5231956 | 0.88 | CNR1 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355886-B1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2007-07-11 | — | — | EP | disclosed |
| US-20040082607-A1 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082607-A1 | Fused heterocyclic compounds | DPP7, DPP4, METAP1 | DPP4 2/4885LMNA 1764/4885CYP1A2 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.