SCHEMBL523129

SCHEMBL523129

C=C(CCCNC(C)C)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.37
ALDH1A1 P00352 4/20 0.37
TDP1 Q9NUW8 2/20 0.36
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 2/20 0.35
CYP2C19 P33261 2/20 0.35
MEN1 O00255 1/20 0.35
CYP2C9 P11712 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ARG1 P05089 1/20 0.34
ARG2 P78540 1/20 0.34
TET2 Q6N021 3/20 0.33
POLB P06746 1/20 0.33
TET3 O43151 1/20 0.33
TET1 Q8NFU7 1/20 0.33
TBXAS1 P24557 1/20 0.33
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL638323 0.94 KDM4E (0.39) KDM4EALDH1A1TDP1CYP1A2CYP2D6
SCHEMBL637242 0.88 KDM4E (0.36) KDM4EALDH1A1TDP1CYP1A2CYP2D6
SCHEMBL11670295 0.82 ARG1 (0.33) KDM4EALDH1A1TDP1ARG1ARG2
SCHEMBL5255471 0.79 LMNA (0.46) ALDH1A1TDP1MEN1KMT2AALOX15
SCHEMBL642265 0.77 CYP2D6 (0.38) KDM4EALDH1A1TDP1CYP2D6CYP2C19
SCHEMBL337280 0.77 KDM4A (0.38) KDM4EALDH1A1TDP1MEN1KMT2A
SCHEMBL329452 0.76 ARG1 (0.35) KDM4EALDH1A1TDP1CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL8005993 0.75 KDM4A (0.41) KDM4EALDH1A1TDP1MEN1KMT2A
SCHEMBL22338049 0.74 ADRB2 (0.33) TDP1HSD17B10
SCHEMBL3282730 0.74 TET2 (0.38) KDM4EALDH1A1TDP1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070113353-A1 Polymeric Surface Treatment Compositions THE CLOROX COMPANY 2007-05-24 US claimed
EP-2605853-B1 PROCESS FOR IMPROVING THE STORAGE STABILITY OF AQUEOUS COMPOSITE PARTICLE DISPERSIONS BASF SE (DE) 2017-04-19 EP disclosed
US-20160160096-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION NITTO DENKO CORPORATION (JP) 2016-06-09 US disclosed
US-9186441-B2 Surface treating agent, filtering material for filter, and blood treatment filter TERUMO KABUSHIKI KAISHA (JP) 2015-11-17 US disclosed
EP-1431356-B1 Use of aqueous dipersion of particles made up of polymerisate and fine inorganic solid material for priming mineral substrates BASF SE (DE) 2015-05-13 EP disclosed
EP-2528978-B1 COATING COMPOSITION CONTAINING COMPOSITE PARTICLES BASF SE (DE) 2013-11-13 EP disclosed
EP-2337803-B1 METHOD FOR PRODUCING POLYMER PARTICLES BY EMULSION POLYMERIZATION BASF SE (DE) 2013-09-25 EP disclosed
EP-2605853-A1 PROCESS FOR IMPROVING THE STORAGE STABILITY OF AQUEOUS COMPOSITE PARTICLE DISPERSIONS BASF SE (DE) 2013-06-26 EP disclosed
EP-2419456-B1 METHOD FOR PRODUCING AN AQUEOUS COMPOSITE PARTICLE DISPERSION BASF SE (DE) 2013-01-23 EP disclosed
EP-2528978-A1 COATING MEANS COMPRISING COMPOSITE PARTICLES BASF SE (DE) 2012-12-05 EP disclosed
EP-1431356-A2 Use of aqueous dipersion of particles made up of polymerisate and fine inorganic solid material for priming mineral substrates Basf AG (DE) 2004-06-23 EP disclosed
EP-1401902-A1 METHOD FOR PRODUCING AN AQUEOUS DISPERSION OF PARTICLES COMPOSED OF A POLYMER AND A FINE-PARTICLE INORGANIC SOLID BASF AKTIENGESELLSCHAFT (DE) 2004-03-31 EP disclosed
WO-2003000760-A1 METHOD FOR PRODUCING AN AQUEOUS DISPERSION OF PARTICLES COMPOSED OF A POLYMER AND A FINE-PARTICLE INORGANIC SOLID BASF AKTIENGESELLSCHAFT (DE) 2003-01-03 WO disclosed
EP-1235869-A1 METHOD FOR PRODUCING AN AQUEOUS DISPERSION OF PARTICLES THAT ARE MADE UP OF POLYMERS AND INORGANIC SOLID MATTER WHICH CONSISTS OF FINE PARTICLES BASF AKTIENGESELLSCHAFT (DE) 2002-09-04 EP disclosed
WO-2001029106-A1 METHOD FOR PRODUCING AN AQUEOUS DISPERSION OF PARTICLES THAT ARE MADE UP OF POLYMERS AND INORGANIC SOLID MATTER WHICH CONSISTS OF FINE PARTICLES BASF AKTIENGESELLSCHAFT (DE) 2001-04-26 WO disclosed
EP-0417091-B1 AQUEOUS COATING COMPOSITIONS VALSPAR CORP (US) 1994-12-14 EP disclosed
US-5296525-A Addition-condensating copolymer containing an epoxy resin THE VALSPAR CORPORATION (US) 1994-03-22 US disclosed
EP-0417091-A4 AQUEOUS COATING COMPOSITIONS 1992-03-18 EP disclosed
EP-0417091-A1 AQUEOUS COATING COMPOSITIONS. VALSPAR CORP (US) 1991-03-20 EP disclosed
WO-1989001498-A1 AQUEOUS COATING COMPOSITIONS THE VALSPAR CORPORATION (US) 1989-02-23 WO disclosed