Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5236800 | 0.89 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL4671695 | 0.89 | KMT2A (0.45) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL5233534 | 0.89 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL5238965 | 0.88 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL5233429 | 0.84 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL5235530 | 0.83 | KMT2A (0.44) | ALDH1A1KMT2AL3MBTL1RAB9ATDP1 | |
| SCHEMBL5235899 | 0.78 | KMT2A (0.41) | ALDH1A1TSHRMAPK1KMT2AL3MBTL1 | |
| SCHEMBL6167072 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL5425216 | 0.76 | KMT2A (0.60) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL6865331 | 0.76 | KMT2A (0.60) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990654-B1 | SUBSTITUTED CYCLOBUTYLAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2007-11-14 | — | — | EP | disclosed |
| US-6448266-B1 | COMPOUNDS SUCH AS 2-AMINO-7-(3-(3-AMINO-1-FLUOROCYCLOBUTAN-3-YL)PYRROLIDIN-1-YL)-6-FLUORO-1-(2-FLUORO-1-CYCLOPROPYL)-8-METHYL-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID; ANTIBACTERIAL ACTIVITY; STAPHYLOCOCCUS, PNEUMOCOCCUS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-09-10 | — | — | US | disclosed |
| EP-0990654-A1 | SUBSTITUTED CYCLOBUTYLAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |