Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.42 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164665 | 0.81 | NPFFR1 (0.48) | KMT2AL3MBTL1NPFFR1NPFFR2 | |
| SCHEMBL4671695 | 0.79 | KMT2A (0.45) | ALDH1A1TSHRMAPK1KMT2AL3MBTL1 | |
| SCHEMBL9142209 | 0.78 | SIGMAR1 (0.46) | ALDH1A1TSHRMAPK1KMT2AL3MBTL1 | |
| SCHEMBL5233534 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPK1KMT2AL3MBTL1 | |
| SCHEMBL6865331 | 0.77 | KMT2A (0.60) | ALDH1A1TSHRMAPK1KMT2AL3MBTL1 | |
| SCHEMBL5425216 | 0.77 | KMT2A (0.60) | ALDH1A1TSHRMAPK1KMT2AL3MBTL1 | |
| SCHEMBL5232248 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPK1KMT2AL3MBTL1 | |
| SCHEMBL5238965 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPK1KMT2AL3MBTL1 | |
| SCHEMBL4713895 | 0.76 | KMT2A (0.47) | MAPK1KMT2AL3MBTL1LMNAHPGD | |
| SCHEMBL4713900 | 0.76 | KMT2A (0.47) | MAPK1KMT2AL3MBTL1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1134219-B1 | CYCLOALKYL-SUBSTITUTED AMINOMETHYLPYRROLIDINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-6573260-B1 | Antibiotics | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1134219-A1 | CYCLOALKYL-SUBSTITUTED AMINOMETHYLPYRROLIDINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |