Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306197 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL11845673 | 0.85 | — | — | |
| SCHEMBL11142350 | 0.76 | ALDH1A1 (0.46) | HSD11B1ALDH1A1LMNAHPGDHIF1A | |
| SCHEMBL11531912 | 0.70 | ALDH1A1 (0.35) | ALDH1A1LMNA | |
| SCHEMBL10625679 | 0.66 | L3MBTL1 (0.40) | ALDH1A1 | |
| SCHEMBL11671846 | 0.66 | ALDH1A1 (0.40) | HSD11B1ALDH1A1LMNAHPGD | |
| SCHEMBL11402517 | 0.66 | MBTD1 (0.36) | ALDH1A1LMNA | |
| SCHEMBL23047083 | 0.65 | — | — | |
| SCHEMBL4674255 | 0.65 | — | — | |
| SCHEMBL9656113 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812080-A2 | GPR41 AND MODULATORS THEREOF FOR THE TREATMENT OF INSULIN-RELATED DISORDERS | Arena Pharmaceuticals, Inc. (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006052566-A2 | GPR41 AND MODULATORS THEREOF FOR THE TREATMENT OF INSULIN-RELATED DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2006-05-18 | — | — | WO | disclosed |