SCHEMBL5232805

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5236226	0.96	PTGDR2 (0.36)	PTGDR2TP53FAAHPOLBRXFP1
	SCHEMBL5231048	0.90	TSHR (0.36)	POLBKDM4EHPGDTSHRHSD17B10
	SCHEMBL5275959	0.90	RORA (0.37)	KDM4ETSHRHSD17B10PTGER4DPP4
	SCHEMBL5237350	0.89	RORA (0.37)	TP53POLBMAPTKDM4ETSHR
	SCHEMBL5230679	0.89	DPP4 (0.36)	TP53MAPTKDM4ECYP1A2CYP3A4
	SCHEMBL5239523	0.89	RORA (0.42)	PTGDR2FAAHPPARG
	SCHEMBL5238703	0.89	LMNA (0.39)	POLBDPP4THRB
	SCHEMBL5231638	0.89	TSHR (0.37)	POLBKDM4EHPGDTSHRHSD17B10
	SCHEMBL5236402	0.89	PGR (0.40)	TP53MAPTKDM4EHSD17B10DPP4
	SCHEMBL5231951	0.89	POLB (0.34)	TP53POLBMAPTKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.