Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22291084 | 0.95 | LMNA (0.53) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5234751 | 0.86 | GPR119 (0.52) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL31544598 | 0.86 | MAPT (0.61) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14711349 | 0.84 | SMN1; SMN2 (0.58) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5573222 | 0.84 | MAPT (0.76) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6978816 | 0.84 | SMN1; SMN2 (0.61) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1136833 | 0.83 | MAPT (0.64) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3807661 | 0.83 | MAPT (0.64) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1019005 | 0.82 | MAPT (0.62) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL20306312 | 0.82 | MAPT (0.62) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |