Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.44 |
| ▸ | HTR3B | O95264 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551200 | 0.94 | ALDH1A1 (0.59) | ALDH1A1TSHRHSD17B10USP2HTT | |
| SCHEMBL16564077 | 0.86 | HTT (0.57) | ALDH1A1TSHRHSD17B10HTTMAPT | |
| SCHEMBL10505311 | 0.86 | HTT (0.61) | ALDH1A1TSHRHSD17B10HTTMAPT | |
| SCHEMBL2201934 | 0.84 | HTT (0.64) | ALDH1A1TSHRHSD17B10HTTMAPT | |
| SCHEMBL5234585 | 0.83 | ALDH1A1 (0.58) | ALDH1A1TSHRHSD17B10USP2CHRNB2 | |
| SCHEMBL3342329 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10USP2ADRB1 | |
| SCHEMBL64895 | 0.82 | HPGD (0.51) | ALDH1A1TSHRHSD17B10USP2CHRNB2 | |
| SCHEMBL334256 | 0.81 | ALDH1A1 (0.64) | ALDH1A1TSHRHSD17B10USP2CHRNB2 | |
| SCHEMBL25803069 | 0.81 | ALDH1A1 (0.63) | ALDH1A1TSHRHSD17B10USP2ADRB1 | |
| SCHEMBL5235280 | 0.79 | TSHR (0.54) | ALDH1A1TSHRHSD17B10USP2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |