Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.46 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551200 | 0.87 | ALDH1A1 (0.59) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| SCHEMBL10605457 | 0.84 | RAB9A (0.61) | ALDH1A1TSHRHSD17B10HSD17B3HRH2 | |
| SCHEMBL11763488 | 0.84 | RAB9A (0.61) | ALDH1A1TSHRHSD17B10HSD17B3HRH2 | |
| SCHEMBL25803069 | 0.83 | ALDH1A1 (0.63) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| SCHEMBL11834203 | 0.83 | ALDH1A1 (0.49) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| Hydrochloric Acid SCHEMBL10623684 | 0.83 | RAB9A (0.60) | ALDH1A1USP2TSHRHSD17B10HSD17B3 | |
| SCHEMBL13069858 | 0.83 | HDAC3 (0.59) | TSHRHSD17B10HSD17B3MEN1KMT2A | |
| SCHEMBL1978734 | 0.83 | GSK3B (0.67) | ALDH1A1HSD17B10HSD17B3MEN1KMT2A | |
| SCHEMBL27873720 | 0.82 | ALDH1A1 (0.51) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| SCHEMBL5233397 | 0.82 | ALDH1A1 (0.54) | ALDH1A1USP2TSHRHSD17B10ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024172156-A1 | COMPOUND HAVING BRASSINOSTEROID-LIKE ACTIVITY | 国立大学法人東海国立大学機構 | 2024-08-22 | — | — | WO | disclosed |
| US-20100063047-A1 | AMINOPYRIMIDINE INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063047-A1 | AMINOPYRIMIDINE INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE | HRH4, HRH2, HRH3 | ALDH1A1 1332/4885USP2 3593/4885TSHR 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.