Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.49 |
| ▸ | HTR3B | O95264 | 3/20 | 0.49 |
| ▸ | HTR3A | P46098 | 3/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233397 | 0.94 | ALDH1A1 (0.54) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| SCHEMBL3342329 | 0.87 | ALDH1A1 (0.56) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| SCHEMBL25803069 | 0.86 | ALDH1A1 (0.63) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| SCHEMBL10505311 | 0.84 | HTT (0.61) | ALDH1A1TSHRHSD17B10GSK3BKDM4E | |
| SCHEMBL16564077 | 0.84 | HTT (0.57) | ALDH1A1TSHRHSD17B10GSK3BKDM4E | |
| SCHEMBL14123719 | 0.83 | GSK3B (0.69) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| SCHEMBL2201934 | 0.83 | HTT (0.64) | ALDH1A1TSHRHSD17B10GSK3BKDM4E | |
| SCHEMBL21477423 | 0.83 | ALDH1A1 (0.55) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| Bromide SCHEMBL14054623 | 0.82 | GSK3B (0.67) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| Bromide SCHEMBL8084816 | 0.82 | GSK3B (0.67) | ALDH1A1USP2TSHRHSD17B10ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101193867-A | N-substituted benzimidazolyl c-Kit inhibitors and combinatorial benzimidazole libraries | OSI PHARM INC (US) | 2008-06-04 | — | — | CN | claimed |
| CN-102533002-B | Solid ink containing ketone wax and side chain acid amides | Xerox Corp. (US) Patent Dept. 020 Xerox Square 100 Clinton Avenue Rochester New (US) | 2016-01-27 | — | — | CN | disclosed |
| CN-103936650-B | Acid imide Phenylpiperazine derivatives and salt, preparation method and purposes | GUANGZHOU MEDICAL UNIVERSITY (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-102234457-B | Fluorescent ink compositions and fluorescent particles | XEROX CORP | 2014-12-24 | — | — | CN | disclosed |
| CN-101899238-B | Method of making a pigmented phase change ink with dispersant and synergist | Xerox Corp. (US) Patent Dept. 020 Xerox Square 100 Clinton Avenue Rochester New (US) | 2014-10-01 | — | — | CN | disclosed |
| CN-103936650-A | Imide phenylpiperazine derivatives as well as salts, preparation method and application of imide phenylpiperazine derivatives | UNIV GUANGZHOU MEDICAL | 2014-07-23 | — | — | CN | disclosed |
| CN-101460237-B | Modified membrane | DOW GLOBAL TECHNOLOGIES INC | 2013-09-04 | — | — | CN | disclosed |
| CN-102234457-A | Fluorescent ink compositions and fluorescent particles | XEROX CORP | 2011-11-09 | — | — | CN | disclosed |
| CN-101460237-A | Modified membrane | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-06-17 | — | — | CN | disclosed |
| CN-101378757-A | Thiadiazole derivatives for the treatment of neuro degenerative diseases | REMYND NV (BE) | 2009-03-04 | — | — | CN | disclosed |
| CN-101193867-A | N-substituted benzimidazolyl c-Kit inhibitors and combinatorial benzimidazole libraries | OSI PHARM INC (US) | 2008-06-04 | — | — | CN | disclosed |
| CN-1243567-C | Growth hormone secretagogues | LILLY CO ELI (US) | 2006-03-01 | — | — | CN | disclosed |
| CN-1553900-A | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents | ��ʱ��ʩ����ҩ��˾ | 2004-12-08 | — | — | CN | disclosed |
| CN-1276727-A | Growth hormone secretagogues | LILLY CO ELI (US) | 2000-12-13 | — | — | CN | disclosed |
| CN-1251523-A | Sulfonamide derivatives | LILLY CO ELI (US) | 2000-04-26 | — | — | CN | disclosed |
| EP-0836599-A1 | 1,6-DISUBSTITUTED ISOCHROMANS FOR TREATMENT OF MIGRAINE HEADACHES | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002259-A1 | 1,6-DISUBSTITUTED ISOCHROMANS FOR TREATMENT OF MIGRAINE HEADACHES | PHARMACIA & UPJOHN COMPANY (US) | 1997-01-23 | — | — | WO | disclosed |