Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 10/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231178 | 0.91 | CYP2D6 (0.42) | KMT2AHCRTR1HCRTR2SIGMAR1 | |
| SCHEMBL5233381 | 0.90 | HCRTR1 (0.41) | HCRTR1HCRTR2SIGMAR1 | |
| SCHEMBL5237863 | 0.90 | SIGMAR1 (0.41) | ALDH1A1HPGDHCRTR1HCRTR2SIGMAR1 | |
| SCHEMBL5235325 | 0.89 | HCRTR1 (0.40) | KMT2AHCRTR1HCRTR2SIGMAR1LMNA | |
| SCHEMBL5237039 | 0.89 | HCRTR1 (0.40) | HCRTR1HCRTR2SIGMAR1 | |
| SCHEMBL5230115 | 0.89 | HCRTR1 (0.40) | HCRTR1HCRTR2SIGMAR1 | |
| SCHEMBL5234742 | 0.89 | HCRTR1 (0.40) | ALDH1A1HCRTR1HCRTR2SIGMAR1 | |
| SCHEMBL5232859 | 0.89 | HCRTR1 (0.40) | HCRTR1HCRTR2SIGMAR1LMNA | |
| SCHEMBL5236854 | 0.89 | HPGD (0.43) | ALDH1A1HPGDKMT2AHCRTR1HCRTR2 | |
| SCHEMBL5233648 | 0.89 | HCRTR1 (0.42) | ALDH1A1HCRTR1HCRTR2SIGMAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-A2 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-03-14 | — | — | EP | claimed |
| WO-2005121145-A2 | OCTAHYDRO-PYRROLO[3,4-C] DERIVATIVES AND THEIR USE AS ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-12-22 | — | — | WO | claimed |