Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 4/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 5/20 | 0.32 |
| ▸ | CPN1 | P15169 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237679 | 0.94 | SIGMAR1 (0.45) | SIGMAR1HRH3HRH4KMT2ANAAA | |
| SCHEMBL9676206 | 0.85 | SIGMAR1 (0.52) | SIGMAR1HRH3HRH4KMT2ANAAA | |
| SCHEMBL9675697 | 0.83 | SIGMAR1 (0.59) | SIGMAR1HRH3HRH4KMT2ANAAA | |
| SCHEMBL6050192 | 0.82 | HRH3 (0.42) | HRH3HRH4KMT2ANAAAACP1 | |
| SCHEMBL2921249 | 0.81 | HRH3 (0.41) | SIGMAR1HRH3HRH4KMT2ANAAA | |
| SCHEMBL13282815 | 0.80 | HRH3 (0.47) | HRH3HRH4KMT2ANAAAACP1 | |
| Hydrochloric Acid SCHEMBL30911772 | 0.80 | HRH3 (0.41) | SIGMAR1HRH3HRH4KMT2ANAAA | |
| SCHEMBL5233843 | 0.79 | CHRNB2 (0.41) | SIGMAR1HRH3HRH4EEDCHRNB2 | |
| SCHEMBL9727916 | 0.79 | SIGMAR1 (0.42) | SIGMAR1HRH3HRH4KMT2ANAAA | |
| SCHEMBL5234543 | 0.79 | HRH3 (0.42) | HRH3HRH4KMT2ANAAAACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |