Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 8/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 7/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 7/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 7/20 | 0.41 |
| ▸ | PSMA1 | P25786 | 7/20 | 0.41 |
| ▸ | PSMA2 | P25787 | 7/20 | 0.41 |
| ▸ | PSMA3 | P25788 | 7/20 | 0.41 |
| ▸ | PSMA4 | P25789 | 7/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 7/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 7/20 | 0.41 |
| ▸ | PSMA5 | P28066 | 7/20 | 0.41 |
| ▸ | PSMB4 | P28070 | 7/20 | 0.41 |
| ▸ | PSMB6 | P28072 | 7/20 | 0.41 |
| ▸ | PSMB10 | P40306 | 7/20 | 0.41 |
| ▸ | PSMB3 | P49720 | 7/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 7/20 | 0.41 |
| ▸ | PSMA6 | P60900 | 7/20 | 0.41 |
| ▸ | PSMA8 | Q8TAA3 | 7/20 | 0.41 |
| ▸ | PSMB7 | Q99436 | 7/20 | 0.41 |
| ▸ | LONP1 | P36776 | 8/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28766234 | 0.79 | PSMB11 (0.41) | PSMB5PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL523433 | 0.79 | CYP1A2 (0.42) | CPA1ECE1CTRB1CYP1A2 | |
| SCHEMBL523436 | 0.79 | CYP1A2 (0.42) | CPA1ECE1CTRB1CYP1A2 | |
| SCHEMBL27872649 | 0.79 | PSMB11 (0.41) | PSMB5PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL524867 | 0.75 | CPA1 (0.42) | CPA1ECE1CTRB1CYP1A2 | |
| SCHEMBL2635827 | 0.72 | CPA1 (0.50) | CPA1CTRB1CYP1A2 | |
| SCHEMBL28611443 | 0.70 | POLB (0.43) | PSMB5PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL10512884 | 0.69 | TSHR (0.55) | ALDH1A1POLBLMNATSHRCYP1A2 | |
| SCHEMBL28766231 | 0.69 | POLB (0.40) | PSMB5PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL28602834 | 0.69 | SLC7A5 (0.38) | PSMB5PSMB11PSMA7PSMB1PSMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293512-B2 | Polypeptide having activity of aminoacyl-tRNA synthetase and use thereof | RIKEN (JP) | 2012-10-23 | — | — | US | disclosed |
| US-20120028330-A1 | POLYPEPTIDE HAVING ACTIVITY OF AMINOACYL-tRNA SYNTHETASE AND USE THEREOF | RIKEN (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20090226966-A1 | Polypeptide having activity of aminoacyl-tRNA synthetase and use thereof | RIKEN (JP) | 2009-09-10 | — | — | US | disclosed |