Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 6/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 5/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 5/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.41 |
| ▸ | PSMA1 | P25786 | 5/20 | 0.41 |
| ▸ | PSMA2 | P25787 | 5/20 | 0.41 |
| ▸ | PSMA3 | P25788 | 5/20 | 0.41 |
| ▸ | PSMA4 | P25789 | 5/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 5/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 5/20 | 0.41 |
| ▸ | PSMA5 | P28066 | 5/20 | 0.41 |
| ▸ | PSMB4 | P28070 | 5/20 | 0.41 |
| ▸ | PSMB6 | P28072 | 5/20 | 0.41 |
| ▸ | PSMB10 | P40306 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28766231 | 0.89 | POLB (0.40) | POLBALDH1A1CTSLCYP1A2CYP2C9 | |
| SCHEMBL28766234 | 0.88 | PSMB11 (0.41) | POLBALDH1A1CTSLCYP1A2CYP2C9 | |
| SCHEMBL27872649 | 0.88 | PSMB11 (0.41) | POLBALDH1A1CTSLCYP1A2CYP2C9 | |
| SCHEMBL28613880 | 0.87 | POLB (0.41) | POLBALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28614526 | 0.82 | RAB9A (0.46) | POLBALDH1A1MEN1KMT2A | |
| SCHEMBL28881741 | 0.80 | ALDH1A1 (0.42) | POLBALDH1A1CTSLCYP1A2CYP2C9 | |
| SCHEMBL28602834 | 0.79 | SLC7A5 (0.38) | CTSLPSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL28767441 | 0.74 | TSHR (0.41) | POLBALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28256496 | 0.74 | PSMB5 (0.42) | POLBALDH1A1CTSLCYP1A2CYP2C9 | |
| SCHEMBL28614528 | 0.71 | PPARG (0.47) | ALDH1A1CYP2C9ATMCYP3A4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008665-B | Compound with tumor proliferation inhibition function and preparation method and application thereof | 北京大学 | 2021-03-16 | — | — | CN | disclosed |