Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.34 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.34 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.34 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.34 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.34 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.34 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.34 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.34 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.34 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.34 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.34 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27872649 | 0.90 | PSMB11 (0.41) | TBXAS1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL28766234 | 0.90 | PSMB11 (0.41) | TBXAS1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL28614526 | 0.86 | RAB9A (0.46) | KMT2ARAB9AKDM4E | |
| SCHEMBL28611443 | 0.79 | POLB (0.43) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL28766231 | 0.75 | POLB (0.40) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL28613880 | 0.71 | POLB (0.41) | KMT2AKDM4E | |
| SCHEMBL523434 | 0.69 | PSMB5 (0.41) | TBXAS1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL276571 | 0.69 | SLC7A5 (0.55) | SLC7A5FOLH1NAALAD2ESR1ESR2 | |
| SCHEMBL9754096 | 0.69 | SLC7A5 (0.55) | SLC7A5FOLH1NAALAD2KMT2AESR1 | |
| SCHEMBL276572 | 0.69 | SLC7A5 (0.55) | SLC7A5FOLH1NAALAD2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008665-B | Compound with tumor proliferation inhibition function and preparation method and application thereof | 北京大学 | 2021-03-16 | — | — | CN | disclosed |