Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.56 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.56 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | HTR3B | O95264 | 1/20 | 0.56 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.56 |
| ▸ | CHRNG | P07510 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524734 | 1.00 | ALDH1A1 (0.56) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| Cyanide SCHEMBL27908616 | 0.95 | ALDH1A1 (0.52) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL28797122 | 0.90 | ALDH1A1 (0.55) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL30618802 | 0.83 | ALDH1A1 (0.64) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL29766108 | 0.83 | ALDH1A1 (0.64) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL30866542 | 0.82 | CHRNA7 (0.62) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL157172 | 0.82 | CHRNA7 (0.62) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5249340 | 0.82 | CHRNA7 (0.62) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL29173751 | 0.82 | CHRNA7 (0.62) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3563193 | 0.81 | CHRNB2 (0.67) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100518823-C | Hapten-carrier conjugates and uses thereof | CYTOS BIOTECHNOLOGY AG (CH) | 2009-07-29 | — | — | CN | claimed |
| US-7452541-B2 | Hapten-carrier conjugates and uses thereof | CYTOS BIOTECHNOLOGY AG (CH) | 2008-11-18 | — | — | US | claimed |
| CN-1668331-A | Hapten-carrier conjugates and uses thereof | CYTOS BIOTECHNOLOGY AG (CH) | 2005-09-14 | — | — | CN | claimed |
| US-6932971-B2 | Hapten-carrier conjugates and uses thereof | CYTOS BIOTECHNOLOGY AG (CH) | 2005-08-23 | — | — | US | claimed |
| US-4115539-A | RADIOIMMUNOASSAY, REACTION PRODUCT WITH ISOCYANATES | UNION CARBIDE CORPORATION (US) | 1978-09-19 | — | — | US | claimed |
| JP-55038309-A | — | — | None | — | — | JP | disclosed |
| WO-2023157150-A1 | USE OF POLYSACCHARIDE DERIVATIVE | 持田製薬株式会社 | 2023-08-24 | — | — | WO | disclosed |
| CN-110818724-B | Pyridone and azapyridone compounds and methods of use | 吉利德康涅狄格有限公司 | 2020-11-13 | — | — | CN | disclosed |
| US-20200236936-A1 | (S)-5-ETHYNYL-ANABASINE, DERIVATIVES THEREOF, AND RELATED COMPOSITIONS AND METHODS OF MAKING AND USING | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2020-07-30 | — | — | US | disclosed |
| US-10667515-B2 | (S)-5-ethynyl-anabasine, derivatives thereof, and related compositions and methods of making and using | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-06-02 | — | — | US | disclosed |
| CN-107253963-B | Pyridone and azapyridone compounds and methods of use | 吉利德康涅狄格有限公司 | 2020-04-14 | — | — | CN | disclosed |
| CN-110818724-A | Pyridone and azapyridone compounds and methods of use | 吉利德康涅狄格有限公司 | 2020-02-21 | — | — | CN | disclosed |
| WO-1999061054-A1 | NICOTINE IMMUNOGEN | INDEPENDENT PHARMACEUTICA AB (SE) | 1999-12-02 | — | — | WO | disclosed |
| EP-0569490-A4 | — | — | 1994-04-06 | — | — | EP | disclosed |
| EP-0569490-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR IMMUNOASSAYS FOR COTININE | ABBOTT LABORATORIES (US) | 1993-11-18 | — | — | EP | disclosed |
| US-5164504-A | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR IMMUNOASSAYS FOR COTININE DERIVATIVES | ABBOTT LABORATORIES (US) | 1992-11-17 | — | — | US | disclosed |
| WO-1992012975-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR IMMUNOASSAYS FOR COTININE | ABBOTT LABORATORIES (US) | 1992-08-06 | — | — | WO | disclosed |
| US-4243605-A | RADIOIMMUNOASSAY, LABELS | UNION CARBIDE CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |
| JP-S5538309-A | NICOTINE DERIVATIVE | JAPAN TOBACCO INC | 1980-03-17 | — | — | JP | disclosed |
| US-4115539-A | RADIOIMMUNOASSAY, REACTION PRODUCT WITH ISOCYANATES | UNION CARBIDE CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10667515-B2 | (S)-5-ethynyl-anabasine, derivatives thereof, and related compositions and methods of making and using | AAAS, NANS, CIAPIN1 | ALDH1A1 2014/4885CHRNA7 2246/4885CHRNB2 2259/4885 |
| US-20200236936-A1 | (S)-5-ETHYNYL-ANABASINE, DERIVATIVES THEREOF, AND RELATED COMPOSITIONS AND METHODS OF MAKING AND USING | AAAS, NANS, CIAPIN1 | ALDH1A1 2014/4885CHRNA7 2246/4885CHRNB2 2259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.