Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228396 | 0.89 | KMT2A (0.34) | — | |
| SCHEMBL5234503 | 0.88 | BRS3 (0.35) | PARP1MAPK11MAPK14TBK1 | |
| SCHEMBL5234986 | 0.88 | BRS3 (0.35) | PARP1MAPK11MAPK14TBK1 | |
| SCHEMBL5232338 | 0.87 | S1PR1 (0.34) | PARP1 | |
| SCHEMBL5235412 | 0.87 | NAMPT (0.31) | PARP1 | |
| SCHEMBL5236797 | 0.84 | — | — | |
| SCHEMBL5236128 | 0.84 | NPC1 (0.34) | — | |
| SCHEMBL5233446 | 0.84 | NPC1 (0.35) | — | |
| SCHEMBL5236136 | 0.84 | — | — | |
| SCHEMBL5234344 | 0.83 | ESRRA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730116-B1 | 4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORP (US) | 2007-09-05 | — | — | EP | claimed |