Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5229387 | 0.92 | SMN1; SMN2 (0.35) | KMT2AALDH1A1KDM4EOPRM1MEN1 | |
| SCHEMBL5233446 | 0.92 | NPC1 (0.35) | KMT2AALDH1A1USP2KDM4EMEN1 | |
| SCHEMBL5232338 | 0.91 | S1PR1 (0.34) | ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5235412 | 0.91 | NAMPT (0.31) | — | |
| SCHEMBL5238208 | 0.90 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5236387 | 0.90 | KDM4E (0.39) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL5236015 | 0.90 | KDM4E (0.43) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL5236136 | 0.89 | — | — | |
| SCHEMBL5236924 | 0.89 | RORC (0.35) | KMT2ARORC | |
| SCHEMBL5234510 | 0.89 | PARP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730116-B1 | 4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORP (US) | 2007-09-05 | — | — | EP | claimed |